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A Shared Biology Underlies 5 Major Fatigue-Causing Illnesses, Scientists Suggest

ScienceAlert·September 7, 2026

For some people, rising from bed or completing daily tasks can feel like extricating oneself from quicksand or the grip of a coiling anaconda.  Those with chronic fatigue syndrome, sometimes known as myalgic encephalomyelitis (CFS/ME), suffer from symptoms like extreme and persistent exhaustion and cognitive issues, including 'brain fog'.  CFS/ME is an 'unambiguously biological' condition for which there is no known cause or cure.

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